Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 13/20 | 0.71 |
| ▸ | PIM1 | P11309 | 4/20 | 0.67 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.67 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.58 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.58 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951889 | 0.90 | FYN (0.63) | FYNPIM1PIM2NTRK1NTRK3 | |
| SCHEMBL13234258 | 0.89 | FYN (0.74) | FYNPIM1PIM2NTRK1NTRK3 | |
| SCHEMBL2950800 | 0.89 | FYN (0.71) | FYNPIM1 | |
| SCHEMBL2951116 | 0.87 | FYN (0.67) | FYNPIM1PIM2NTRK1NTRK3 | |
| SCHEMBL4694754 | 0.85 | FYN (0.66) | FYN | |
| SCHEMBL2942616 | 0.85 | PIM1 (0.76) | FYNPIM1NTRK1NTRK3NTRK2 | |
| SCHEMBL13234281 | 0.84 | FYN (0.71) | FYNPIM1NTRK1NTRK3NTRK2 | |
| SCHEMBL18613828 | 0.83 | FYN (1.00) | FYNPIM1PIM2 | |
| SCHEMBL30521822 | 0.83 | FYN (1.00) | FYNPIM1PIM2 | |
| SCHEMBL13234269 | 0.83 | FYN (0.80) | FYNPIM1NTRK1NTRK3NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900739-A1 | Diazolodiazine derivatives as kinase inhibitors | CELLZOME AG (DE) | 2008-03-19 | — | — | EP | claimed |
| WO-2008025822-A1 | DIAZOLODIAZINE DERIVATIVES AS KINASE INHIBITORS | CELLZOME LIMITED (GB) | 2008-03-06 | — | — | WO | claimed |
| EP-1900739-A1 | Diazolodiazine derivatives as kinase inhibitors | CELLZOME AG (DE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2008025822-A1 | DIAZOLODIAZINE DERIVATIVES AS KINASE INHIBITORS | CELLZOME LIMITED (GB) | 2008-03-06 | — | — | WO | disclosed |