Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 13/20 | 0.66 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.66 |
| ▸ | IKBKB | O14920 | 2/20 | 0.65 |
| ▸ | GRK5 | P34947 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18613364 | 0.85 | CAMK2D (0.86) | FYNCAMK2DGRK5 | |
| SCHEMBL4691093 | 0.85 | FYN (0.71) | FYN | |
| SCHEMBL2951889 | 0.83 | FYN (0.63) | FYN | |
| SCHEMBL1054936 | 0.80 | IKBKB (0.80) | FYNIKBKB | |
| SCHEMBL20485648 | 0.79 | FYN (1.00) | FYNCAMK2DGRK5 | |
| SCHEMBL4695467 | 0.79 | FYN (0.72) | FYNCAMK2D | |
| SCHEMBL30521754 | 0.78 | FYN (1.00) | FYNCAMK2DGRK5 | |
| SCHEMBL16331423 | 0.78 | FYN (1.00) | FYNCAMK2DGRK5 | |
| SCHEMBL2942616 | 0.78 | PIM1 (0.76) | FYN | |
| SCHEMBL18613359 | 0.78 | FYN (1.00) | FYNCAMK2DGRK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900739-A1 | Diazolodiazine derivatives as kinase inhibitors | CELLZOME AG (DE) | 2008-03-19 | — | — | EP | claimed |
| WO-2008025822-A1 | DIAZOLODIAZINE DERIVATIVES AS KINASE INHIBITORS | CELLZOME LIMITED (GB) | 2008-03-06 | — | — | WO | claimed |
| EP-1900739-A1 | Diazolodiazine derivatives as kinase inhibitors | CELLZOME AG (DE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2008025822-A1 | DIAZOLODIAZINE DERIVATIVES AS KINASE INHIBITORS | CELLZOME LIMITED (GB) | 2008-03-06 | — | — | WO | disclosed |