Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 18/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694189 | 0.86 | CCR5 (0.53) | CCR5 | |
| SCHEMBL4696272 | 0.85 | CCR5 (0.58) | CCR5 | |
| SCHEMBL4696462 | 0.84 | CCR5 (0.51) | CCR5 | |
| SCHEMBL4695682 | 0.83 | CCR5 (0.54) | CCR5 | |
| SCHEMBL4695463 | 0.82 | CCR5 (0.59) | CCR5 | |
| SCHEMBL4694057 | 0.82 | CCR5 (0.51) | CCR5 | |
| SCHEMBL4695814 | 0.82 | CCR5 (0.59) | CCR5 | |
| SCHEMBL4695329 | 0.82 | CCR5 (0.56) | CCR5 | |
| SCHEMBL4695085 | 0.82 | CCR5 (0.61) | CCR5 | |
| SCHEMBL4696445 | 0.82 | CCR5 (0.57) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |