Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4691975 | 0.94 | GRM1 (0.36) | GRM1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4691276 | 0.90 | GRM1 (0.44) | GRM1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4691273 | 0.90 | GRM1 (0.44) | GRM1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL5539815 | 0.90 | GRM1 (0.38) | GRM1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4692984 | 0.88 | GRM1 (0.47) | GRM1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL5542933 | 0.88 | GRM1 (0.42) | GRM1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL5542942 | 0.88 | GRM1 (0.42) | GRM1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4689299 | 0.87 | GRM1 (0.45) | GRM1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL4691279 | 0.84 | GRM1 (0.38) | GRM1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4694653 | 0.84 | GRM1 (0.43) | GRM1MEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486501-B1 | AMINOMETHYL-SUBSTITUTED THIAZOLOBENZIMIDAZOLE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2008-09-10 | — | — | EP | disclosed |