Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692988 | 0.94 | GRM1 (0.41) | GRM1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL4693604 | 0.93 | GRM1 (0.53) | GRM1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL5539879 | 0.90 | GRM1 (0.41) | GRM1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL4691968 | 0.88 | GRM1 (0.42) | GRM1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL4693608 | 0.88 | GRM1 (0.46) | GRM1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL4689299 | 0.88 | GRM1 (0.45) | GRM1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL4692243 | 0.88 | GRM1 (0.46) | GRM1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL4692237 | 0.88 | GRM1 (0.46) | GRM1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL4694653 | 0.85 | GRM1 (0.43) | GRM1MEN1KMT2AGAATP53 | |
| SCHEMBL5544676 | 0.84 | GRM1 (0.47) | GRM1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486501-B1 | AMINOMETHYL-SUBSTITUTED THIAZOLOBENZIMIDAZOLE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2008-09-10 | — | — | EP | disclosed |