Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 3/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.41 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 2/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | AOC2 | O75106 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4694732 | 0.99 | METTL3 (0.40) | METTL3GRM1ACSS2ITKMAP4K4 | |
| SCHEMBL4693212 | 0.93 | METTL3 (0.41) | METTL3GRM1ACSS2ITKGLS | |
| Hydrochloric Acid SCHEMBL4694736 | 0.92 | METTL3 (0.40) | METTL3GRM1ACSS2ITKGLS | |
| Hydrochloric Acid SCHEMBL4692163 | 0.89 | GRM1 (0.39) | METTL3GRM1ACSS2ITKCNR2 | |
| Hydrochloric Acid SCHEMBL4694679 | 0.87 | METTL3 (0.42) | METTL3GRM1 | |
| Hydrochloric Acid SCHEMBL4694677 | 0.87 | METTL3 (0.42) | METTL3GRM1 | |
| Hydrochloric Acid SCHEMBL4691062 | 0.85 | GRM1 (0.41) | METTL3GRM1ACSS2ITKCNR2 | |
| Hydrochloric Acid SCHEMBL4691070 | 0.85 | GRM1 (0.41) | METTL3GRM1ACSS2ITKCNR2 | |
| Hydrochloric Acid SCHEMBL4692154 | 0.85 | GRM1 (0.45) | METTL3GRM1ACSS2ITKMAP4K4 | |
| SCHEMBL4693193 | 0.82 | GRM1 (0.46) | METTL3GRM1ACSS2ITKCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486501-B1 | AMINOMETHYL-SUBSTITUTED THIAZOLOBENZIMIDAZOLE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2008-09-10 | — | — | EP | claimed |