Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2168382 | 0.89 | LTA4H (0.73) | LTA4HKCNH2 | |
| SCHEMBL4693475 | 0.85 | LTA4H (0.79) | LTA4HKCNH2 | |
| SCHEMBL2171364 | 0.84 | LTA4H (0.61) | LTA4HKCNH2 | |
| SCHEMBL6362970 | 0.81 | LTA4H (0.69) | LTA4HKCNH2 | |
| SCHEMBL4968382 | 0.81 | LTA4H (0.57) | LTA4HKCNH2 | |
| SCHEMBL4693810 | 0.80 | KCNH2 (0.55) | LTA4HKCNH2 | |
| SCHEMBL2168238 | 0.79 | LTA4H (0.75) | LTA4HKCNH2 | |
| SCHEMBL4694062 | 0.78 | LTA4H (0.79) | LTA4HKCNH2 | |
| SCHEMBL4692949 | 0.77 | LTA4H (0.75) | LTA4HKCNH2 | |
| SCHEMBL5709501 | 0.74 | LTA4H (0.55) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660492-B1 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-20 | — | — | EP | claimed |