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Cyclopentane

Cyclopentane

SCHEMBL4692816

C1CCCC1.O=C(O)NC(CCN1CC2CN(C(=O)C3CCC3)C[C@@H]2C1)c1ccccc1

nearest known ligand 0.67

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Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CCR5 P51681 20/20 0.67
▸ CCL5 P13501 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopentane SCHEMBL4694862 0.97 CCR5 (0.65) CCR5CCL5
Cyclopentane SCHEMBL4695507 0.90 CCR5 (0.68) CCR5CCL5
Cyclopentane SCHEMBL4694323 0.86 CCR5 (0.54) CCR5CCL5
Cyclopentane SCHEMBL4694510 0.85 CCR5 (0.57) CCR5
Cyclopentane SCHEMBL4695484 0.85 CCR5 (0.78) CCR5
SCHEMBL4697296 0.83 CCR5 (0.72) CCR5CCL5
SCHEMBL4692082 0.82 CCR5 (0.54) CCR5CCL5
Cyclopentane SCHEMBL4695376 0.82 CCR5 (0.52) CCR5
SCHEMBL4692521 0.82 CCR5 (0.54) CCR5CCL5
Cyclopentane SCHEMBL4692443 0.82 CCR5 (0.61) CCR5CCL5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1761542-B1 OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS HOFFMANN LA ROCHE (CH) 2008-01-02 — — EP claimed