Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3574701 | 0.80 | TDP1 (0.50) | TDP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17553044 | 0.78 | TDP1 (0.53) | TDP1ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL5252374 | 0.76 | TDP1 (0.61) | TDP1ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL22223633 | 0.76 | TDP1 (0.55) | TDP1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL31727 | 0.74 | HSD17B10 (0.55) | TDP1ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL10531193 | 0.74 | TSHR (0.65) | TDP1ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL12748810 | 0.74 | TDP1 (0.57) | TDP1ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL28307480 | 0.74 | TDP1 (0.57) | TDP1ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL5728848 | 0.73 | TDP1 (0.75) | TDP1ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL7912372 | 0.73 | TDP1 (0.67) | TDP1ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874773-A1 | HEXARYLENE AND PENTARYLENE TETRACARBOXYLIC ACID DIIMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006111511-A1 | HEXARYLENE AND PENTARYLENE TETRACARBOXYLIC ACID DIIMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-10-26 | — | — | WO | disclosed |