SCHEMBL7912372

SCHEMBL7912372

O=[N+]([O-])c1ccc2c3ccc([N+](=O)[O-])c4cccc(c5cccc1c52)c43

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.67
ALDH1A1 P00352 7/20 0.63
CYP3A4 P08684 2/20 0.63
ALOX15 P16050 1/20 0.63
HSD17B10 Q99714 1/20 0.63
NPC1 O15118 4/20 0.54
KMT2A Q03164 4/20 0.54
RAB9A P51151 3/20 0.54
MEN1 O00255 3/20 0.54
GAA P10253 2/20 0.54
CTSB P07858 3/20 0.53
CYP1A2 P05177 1/20 0.50
NCOA1 Q15788 1/20 0.49
NCOA3 Q9Y6Q9 1/20 0.49
POLB P06746 2/20 0.48
GPR35 Q9HC97 1/20 0.46
S1PR4 O95977 1/20 0.45
HPGD P15428 1/20 0.45
XBP1 P17861 1/20 0.45
S1PR1 P21453 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1275010 0.92 ALDH1A1 (0.60) TDP1ALDH1A1CYP3A4ALOX15HSD17B10
SCHEMBL17553044 0.89 TDP1 (0.53) TDP1ALDH1A1CYP3A4ALOX15HSD17B10
SCHEMBL10526689 0.86 TDP1 (0.74) TDP1ALDH1A1CYP3A4ALOX15HSD17B10
SCHEMBL19368140 0.86 ALDH1A1 (0.50) TDP1ALDH1A1CYP3A4ALOX15HSD17B10
SCHEMBL19361418 0.84 ALDH1A1 (0.49) TDP1ALDH1A1CYP3A4ALOX15HSD17B10
SCHEMBL28645723 0.83 CDK2 (0.49) TDP1ALDH1A1CYP3A4ALOX15HSD17B10
Ammonia Solution, Strong SCHEMBL6416651 0.81 MEN1 (0.68) TDP1ALDH1A1CYP3A4ALOX15HSD17B10
1-Nitropyrene SCHEMBL339725 0.81 ALDH1A1 (0.57) TDP1ALDH1A1CYP3A4ALOX15HSD17B10
1-Nitropyrene SCHEMBL29450697 0.81 ALDH1A1 (0.57) TDP1ALDH1A1CYP3A4ALOX15HSD17B10
SCHEMBL7788656 0.80 TDP1 (0.80) TDP1ALDH1A1CYP3A4ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed