Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4693608 | 0.95 | GRM1 (0.46) | GRM1MEN1KMT2AGAATP53 | |
| SCHEMBL4692984 | 0.93 | GRM1 (0.47) | GRM1MEN1KMT2AGAATP53 | |
| SCHEMBL5544676 | 0.91 | GRM1 (0.47) | GRM1MEN1KMT2AGAAHTR2C | |
| SCHEMBL4692988 | 0.88 | GRM1 (0.41) | GRM1MEN1KMT2AGAATP53 | |
| SCHEMBL4689299 | 0.86 | GRM1 (0.45) | GRM1MEN1KMT2AGAATP53 | |
| SCHEMBL4692243 | 0.86 | GRM1 (0.46) | GRM1MEN1KMT2AGAATP53 | |
| SCHEMBL4692237 | 0.86 | GRM1 (0.46) | GRM1MEN1KMT2AGAATP53 | |
| SCHEMBL5544673 | 0.84 | GRM1 (0.48) | GRM1 | |
| SCHEMBL5544680 | 0.84 | GRM1 (0.48) | GRM1 | |
| SCHEMBL4691276 | 0.84 | GRM1 (0.44) | GRM1MEN1KMT2AGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486501-B1 | AMINOMETHYL-SUBSTITUTED THIAZOLOBENZIMIDAZOLE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2008-09-10 | — | — | EP | disclosed |