Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 13/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3536223 | 0.86 | PTGER4 (0.69) | PTGER4 | |
| SCHEMBL4686947 | 0.82 | PTGER4 (0.73) | PTGER4 | |
| SCHEMBL3534680 | 0.82 | PTGER4 (0.55) | PTGER4KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL4691619 | 0.80 | PTGER4 (0.58) | PTGER4MEN1KMT2AALDH1A1 | |
| SCHEMBL4693153 | 0.80 | PTGER4 (0.52) | PTGER4LMNA | |
| SCHEMBL4690414 | 0.74 | PTGER4 (0.55) | PTGER4 | |
| SCHEMBL3538824 | 0.73 | PTGER4 (0.73) | PTGER4 | |
| SCHEMBL4693688 | 0.69 | PTGER4 (0.57) | PTGER4 | |
| SCHEMBL4693788 | 0.69 | PTGER4 (0.70) | PTGER4 | |
| SCHEMBL4694643 | 0.68 | PTGER4 (0.58) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | claimed |