Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 13/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3531970 | 0.86 | PTGER4 (0.71) | PTGER4POLB | |
| SCHEMBL4686947 | 0.83 | PTGER4 (0.73) | PTGER4 | |
| SCHEMBL3540319 | 0.82 | PTGER4 (0.56) | PTGER4LMNAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL14199906 | 0.81 | PTGER4 (0.55) | PTGER4PPARGPPARALMNAPOLB | |
| SCHEMBL4691619 | 0.80 | PTGER4 (0.58) | PTGER4PPARGPPARAPOLBNPC1 | |
| SCHEMBL4693864 | 0.80 | PTGER4 (0.51) | PTGER4LMNA | |
| SCHEMBL3538565 | 0.76 | PTGER4 (0.76) | PTGER4 | |
| SCHEMBL3537596 | 0.73 | PTGER4 (0.75) | PTGER4 | |
| SCHEMBL4687523 | 0.73 | PTGER4 (0.55) | PTGER4 | |
| SCHEMBL4693688 | 0.70 | PTGER4 (0.57) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | claimed |