Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13502740 | 0.83 | SPHK1 (0.37) | ALDH1A1CYP2D6KDM4EKMT2ASPHK1 | |
| SCHEMBL5112211 | 0.82 | CNR2 (0.36) | ALDH1A1SMN1; SMN2TP53CTSLCTSB | |
| SCHEMBL20366215 | 0.80 | SPHK1 (0.36) | ALDH1A1CYP2D6KDM4EKMT2ASPHK1 | |
| SCHEMBL21083751 | 0.79 | SPHK1 (0.38) | ALDH1A1CYP2D6KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL30389190 | 0.78 | SPHK1 (0.37) | ALDH1A1KDM4EKMT2ASMN1; SMN2SPHK1 | |
| SCHEMBL21083999 | 0.76 | SPHK1 (0.46) | KDM4EKMT2ASPHK1P2RX7CTSL | |
| SCHEMBL20054142 | 0.76 | PTPN1 (0.37) | ALDH1A1KDM4EKMT2ASMN1; SMN2TP53 | |
| SCHEMBL21083984 | 0.76 | KMT2A (0.37) | ALDH1A1CYP2D6KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL15125084 | 0.76 | SMN1; SMN2 (0.36) | ALDH1A1KDM4EKMT2ASMN1; SMN2TP53 | |
| SCHEMBL20221443 | 0.75 | SPHK1 (0.45) | ALDH1A1KDM4EKMT2ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919469-A2 | PROCESS FOR PREPARING AN ANGIOTENSIN II RECEPTOR ANTAGONIST | Farmaprojects, S.A. (ES) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007017469-A2 | PROCESS FOR PREPARING AN ANGIOTENSIN II RECEPTOR ANTAGONIST | FARMAPROJECTS, S. A. (ES) | 2007-02-15 | — | — | WO | disclosed |