Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3881545 | 0.95 | AURKA (0.70) | AURKA | |
| SCHEMBL3882182 | 0.89 | AURKA (0.79) | AURKA | |
| SCHEMBL4692932 | 0.88 | AURKA (0.72) | AURKA | |
| SCHEMBL3894750 | 0.87 | AURKA (0.84) | AURKA | |
| Hydrochloric Acid SCHEMBL4698082 | 0.86 | AURKA (0.82) | AURKA | |
| SCHEMBL3881075 | 0.86 | AURKA (0.85) | AURKA | |
| SCHEMBL3885418 | 0.86 | AURKA (1.00) | AURKA | |
| SCHEMBL3887141 | 0.85 | AURKA (0.78) | AURKA | |
| Hydrochloric Acid SCHEMBL4696619 | 0.85 | AURKA (0.83) | AURKA | |
| SCHEMBL4696441 | 0.84 | AURKA (1.00) | AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534716-B1 | HETEROBICYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PFIZER ITALIA SRL (IT) | 2008-04-23 | — | — | EP | claimed |