Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754421 | 0.93 | CCR5 (0.78) | CCR5 | |
| SCHEMBL4694496 | 0.90 | CCR5 (0.77) | CCR5 | |
| SCHEMBL3282812 | 0.90 | CCR5 (0.74) | CCR5 | |
| SCHEMBL4750791 | 0.90 | CCR5 (0.74) | CCR5 | |
| Cyclopentane SCHEMBL4750291 | 0.89 | CCR5 (0.86) | CCR5 | |
| SCHEMBL4695642 | 0.89 | CCR5 (0.86) | CCR5 | |
| Cyclopropane SCHEMBL4691484 | 0.89 | CCR5 (0.86) | CCR5 | |
| SCHEMBL14591182 | 0.88 | CCR5 (0.72) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL4696382 | 0.88 | CCR5 (0.71) | CCR5 | |
| SCHEMBL13326684 | 0.87 | CCR5 (0.69) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |