Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 15/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.81 |
| ▸ | THPO | P40225 | 2/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.81 |
| ▸ | MTOR | P42345 | 1/20 | 0.81 |
| ▸ | DRD2 | P14416 | 4/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | BLM | P54132 | 1/20 | 0.79 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | DRD5 | P21918 | 4/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11712694 | 0.89 | DRD1 (1.00) | DRD1HSD17B10THPOMAPK1HIF1A | |
| Bromide SCHEMBL11707024 | 0.88 | KDM4E (1.00) | DRD1HSD17B10THPOMAPK1HIF1A | |
| SCHEMBL9764438 | 0.86 | DRD1 (0.82) | DRD1HSD17B10THPOMAPK1HIF1A | |
| SCHEMBL31676580 | 0.85 | DRD1 (0.81) | DRD1HSD17B10THPOMAPK1HIF1A | |
| Sch-23390 SCHEMBL2916216 | 0.85 | DRD1 (1.00) | DRD1HSD17B10THPOMAPK1HIF1A | |
| Sch-23390 SCHEMBL29797998 | 0.85 | DRD1 (1.00) | DRD1HSD17B10THPOMAPK1HIF1A | |
| Sch-23390 SCHEMBL11107859 | 0.85 | DRD1 (1.00) | DRD1HSD17B10THPOMAPK1HIF1A | |
| SCHEMBL11398674 | 0.85 | DRD1 (1.00) | DRD1HSD17B10THPOMAPK1HIF1A | |
| Sch-23390 SCHEMBL16187032 | 0.85 | DRD1 (1.00) | DRD1HSD17B10THPOMAPK1HIF1A | |
| SCHEMBL20415945 | 0.85 | DRD1 (1.00) | DRD1HSD17B10THPOMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033874-A1 | METHOD OF TREATING COMPULSIVE SELF-INJURIOUS BEHAVIORS | CHIPKIN RICHARD E (US) | 2012-03-15 | — | — | WO | disclosed |
| WO-2011140607-A1 | A METHOD OF TREATMENT AND DIAGNOSIS | KEATING CHARLOTTE L (AU) | 2011-11-17 | — | — | WO | disclosed |