Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 7/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732718 | 0.82 | DHFR (0.52) | DHFR | |
| SCHEMBL4814896 | 0.81 | DHFR (0.70) | DHFR | |
| SCHEMBL5861648 | 0.79 | DHFR (0.57) | DHFR | |
| SCHEMBL9621108 | 0.79 | DHFR (0.51) | DHFR | |
| SCHEMBL11634253 | 0.78 | CA1 (0.72) | DHFR | |
| SCHEMBL4685928 | 0.77 | DHFR (0.61) | DHFR | |
| SCHEMBL3739935 | 0.76 | DHFR (0.61) | DHFR | |
| SCHEMBL3745109 | 0.75 | DHFR (0.80) | DHFR | |
| SCHEMBL11664759 | 0.75 | DHFR (0.78) | DHFR | |
| SCHEMBL13598112 | 0.74 | DHFR (0.57) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549614-A4 | VASCULOSTATIC AGENTS AND METHODS OF USE THEREOF | TARGEGEN INC (US) | 2008-04-16 | — | — | EP | disclosed |
| EP-1549614-A2 | VASCULOSTATIC AGENTS AND METHODS OF USE THEREOF | Targegen, Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004030635-A2 | VASCULOSTATIC AGENTS AND METHODS OF USE THEREOF | TARGEGEN, INC. (US) | 2004-04-15 | — | — | WO | disclosed |