Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 9/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4695168 | 1.00 | NPBWR1 (0.36) | NPBWR1LMNATSHRMCHR1KDM4E | |
| SCHEMBL4142495 | 0.90 | KDM1A (0.38) | NPBWR1LMNATSHRMCHR1UCHL1 | |
| SCHEMBL4142491 | 0.90 | KDM1A (0.38) | NPBWR1LMNATSHRMCHR1UCHL1 | |
| SCHEMBL5260871 | 0.79 | CHRM2 (0.31) | — | |
| SCHEMBL5260866 | 0.79 | CHRM2 (0.31) | — | |
| SCHEMBL4693154 | 0.76 | MEN1 (0.38) | LMNAKDM4E | |
| SCHEMBL4693156 | 0.76 | MEN1 (0.38) | LMNAKDM4E | |
| SCHEMBL4695949 | 0.74 | TMEM97 (0.33) | — | |
| SCHEMBL4696418 | 0.73 | KDM4E (0.39) | NPBWR1LMNAMCHR1KDM4EHRH3 | |
| SCHEMBL4152639 | 0.71 | KDM1A (0.43) | NPBWR1LMNAMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569935-B1 | HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREOF AND USE OF SAME AS MEDICAMENTS, SUCH AS ANTI-BACTERIAL MEDICAMENTS AND BETA-LACTAMASE INHIBITORS | NOVEXEL (FR) | 2008-08-20 | — | — | EP | disclosed |