SCHEMBL4695345

SCHEMBL4695345

CCOC(=O)N[SiH2]NC(N)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.44
GAA P10253 2/20 0.39
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
ALDH1A1 P00352 4/20 0.37
CAD P27708 1/20 0.37
KMT2A Q03164 1/20 0.37
LMNA P02545 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SOAT1 P35610 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
MAPK1 P28482 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KDM4E B2RXH2 1/20 0.33
TRPA1 O75762 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4553719 0.76
SCHEMBL8657641 0.74
SCHEMBL7543688 0.73
SCHEMBL28110736 0.73
SCHEMBL420598 0.73
SCHEMBL27985614 0.73
SCHEMBL32131 0.73 ALOX15 (0.52) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL524824 0.69 ALOX15 (0.54) ALOX15GAAMGAMSIMGAM2
SCHEMBL361310 0.69
Ethyl Hydroxycarbamate SCHEMBL27236962 0.69 ALOX15 (0.52) ALOX15GAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1310514-B1 A silane copolymer and process for preparing the same BARD INC C R (US) 2008-09-10 EP claimed
EP-1129119-B1 SILANE COPOLYMER COATINGS BARD INC C R (US) 2003-04-02 EP claimed
CN-108559725-A placental stem cell populations 人类起源公司 2018-09-21 CN disclosed
CN-101395266-B placental stem cell populations 人类起源公司 2018-06-15 CN disclosed
CN-103525758-B placental stem cell populations 人类起源公司 2018-02-13 CN disclosed
EP-1310514-B1 A silane copolymer and process for preparing the same BARD INC C R (US) 2008-09-10 EP disclosed
US-7029755-B2 Silane copolymer compositions containing active agents C. R. BARD, INC. (US) 2006-04-18 US disclosed
US-6908681-B2 Silane copolymer coatings C.R. BARD, INC. (US) 2005-06-21 US disclosed
US-20030198821-A1 Silane copolymer compositions containing active agents C.R. BARD, INC. 2003-10-23 US disclosed
US-6596401-B1 Polyurethane-urea-silane copolymer along with active agent such as antibiotic for coating medical devices such as catheters or IUDs C. R. BARD INC. 2003-07-22 US disclosed
EP-1310514-A2 A silane copolymer and process for preparing the same C.R. Bard Inc. (US) 2003-05-14 EP disclosed
EP-1129119-B1 SILANE COPOLYMER COATINGS BARD INC C R (US) 2003-04-02 EP disclosed
US-20020128419-A1 Silane copolymer coatings TERRY RICHARD N (US) 2002-09-12 US disclosed
EP-1228146-A1 SILANE COPOLYMER COMPOSITIONS CONTAINING ACTIVE AGENTS C.R. BARD, INC. (US) 2002-08-07 EP disclosed
US-6329488-B1 MEDICAL DEVICES, SUCH CATHETERS HAVING COATING C. R. BARD, INC. 2001-12-11 US disclosed
EP-1129119-A2 SILANE COPOLYMER COATINGS C.R. Bard Inc. (US) 2001-09-05 EP disclosed
WO-2001053414-A1 SILANE COPOLYMER COMPOSITIONS CONTAINING ACTIVE AGENTS C.R. BARD, INC. (US) 2001-07-26 WO disclosed
WO-2000027897-A2 SILANE COPOLYMER COATINGS C.R. BARD, INC. (US) 2000-05-18 WO disclosed