Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.57 |
| ▸ | PGR | P06401 | 6/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 9/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696367 | 0.94 | NR3C1 (0.56) | NR3C1PGRNR3C2 | |
| SCHEMBL5009719 | 0.92 | NR3C1 (0.54) | NR3C1PGRNR3C2 | |
| SCHEMBL5007683 | 0.91 | NR3C1 (0.61) | NR3C1PGRNR3C2 | |
| SCHEMBL5007657 | 0.88 | NR3C1 (0.61) | NR3C1PGRNR3C2 | |
| SCHEMBL14931943 | 0.88 | NR3C1 (0.64) | NR3C1PGRNR3C2 | |
| SCHEMBL4694320 | 0.87 | NR3C1 (0.55) | NR3C1PGRNR3C2 | |
| SCHEMBL5009192 | 0.87 | NR3C1 (0.56) | NR3C1PGRNR3C2 | |
| SCHEMBL5007639 | 0.86 | NR3C1 (0.56) | NR3C1PGRNR3C2 | |
| SCHEMBL4751830 | 0.86 | NR3C1 (0.78) | NR3C1PGRNR3C2 | |
| SCHEMBL1776758 | 0.85 | NR3C1 (0.74) | NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945642-A1 | PYRAZOLO-PYRIMIDINE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | GLAXO GROUP LIMITED (GB) | 2008-07-23 | — | — | EP | claimed |
| WO-2007054294-A1 | PYRAZOLO-PYRIMIDINE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | GLAXO GROUP LIMITED (GB) | 2007-05-18 | — | — | WO | claimed |
| EP-1945642-A1 | PYRAZOLO-PYRIMIDINE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | GLAXO GROUP LIMITED (GB) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007054294-A1 | PYRAZOLO-PYRIMIDINE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | GLAXO GROUP LIMITED (GB) | 2007-05-18 | — | — | WO | disclosed |