Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230928 | 0.77 | KDM4D (0.43) | CDK2CSNK2A1KDM4EALDH1A1LMNA | |
| SCHEMBL5321324 | 0.77 | CDK2 (0.41) | CDK2CSNK2A1KDM4EALDH1A1HPGD | |
| SCHEMBL5321326 | 0.77 | CDK2 (0.41) | CDK2CSNK2A1KDM4EALDH1A1HPGD | |
| SCHEMBL4691830 | 0.76 | CSNK2A1 (0.46) | CDK2CSNK2A1KDM4EALDH1A1LMNA | |
| SCHEMBL5594559 | 0.74 | CSNK2A1 (0.43) | CDK2CSNK2A1KDM4EALDH1A1LMNA | |
| SCHEMBL4695611 | 0.73 | CSNK2A1 (0.41) | CDK2CSNK2A1KDM4EALDH1A1LMNA | |
| SCHEMBL5323810 | 0.72 | KDM4E (0.44) | CDK2CSNK2A1KDM4EALDH1A1LMNA | |
| SCHEMBL18863648 | 0.71 | CDK2 (0.45) | CDK2CSNK2A1KDM4EALDH1A1LMNA | |
| SCHEMBL5438939 | 0.71 | CDK2 (0.48) | CDK2CSNK2A1KDM4EALDH1A1LMNA | |
| SCHEMBL4695582 | 0.69 | CSNK2A1 (0.39) | CDK2CSNK2A1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641800-B1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007101859-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF FOR CONTROLLING PARASITIC FUNGI AND AGENTS CONTAINING THE LATTER | BASF SE (DE) | 2007-09-13 | — | — | WO | disclosed |
| US-20070037828-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-02-15 | — | — | US | disclosed |
| US-20070037828-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-02-15 | — | — | US | disclosed |
| US-20070037828-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-02-15 | — | — | US | disclosed |
| EP-1641800-A1 | PYRAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005000851-A1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037828-A1 | Pyrazolopyrimidines | DPYD, RPLP2, Q6ZSR9 | CDK2 500/4885CSNK2A1 2676/4885KDM4E 3205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.