Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14463715 | 0.82 | ALDH1A1 (0.46) | CSNK2A1LMNATSHRKDM4DALDH1A1 | |
| SCHEMBL5233173 | 0.81 | KDM4E (0.48) | CSNK2A1LMNATSHRKDM4DALDH1A1 | |
| SCHEMBL14257400 | 0.81 | LMNA (0.40) | CSNK2A1LMNATSHRKDM4DALDH1A1 | |
| SCHEMBL5230928 | 0.81 | KDM4D (0.43) | CSNK2A1LMNAKDM4DALDH1A1KDM4E | |
| SCHEMBL5594559 | 0.81 | CSNK2A1 (0.43) | CSNK2A1LMNAKDM4DALDH1A1KDM4E | |
| SCHEMBL4693069 | 0.79 | PDE2A (0.41) | CSNK2A1LMNATSHRALDH1A1KDM4E | |
| SCHEMBL4691830 | 0.77 | CSNK2A1 (0.46) | CSNK2A1LMNAKDM4DALDH1A1KDM4E | |
| SCHEMBL18863648 | 0.76 | CDK2 (0.45) | CSNK2A1LMNAKDM4DALDH1A1KDM4E | |
| SCHEMBL4507101 | 0.74 | KDM4E (0.46) | LMNATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL4695611 | 0.72 | CSNK2A1 (0.41) | CSNK2A1LMNAKDM4DALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694681-B1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2008-03-12 | — | — | EP | disclosed |
| US-20060276478-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2006-12-07 | — | — | US | disclosed |
| EP-1694681-A1 | PYRAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005056556-A1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276478-A1 | Pyrazolopyrimidines | Q6ZSR9, RPLP2, DPYD | CSNK2A1 3066/4885LMNA 4800/4885TSHR 1348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.