Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 7/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071074 | 0.71 | ALDH1A1 (0.46) | PKMF10PLGPLAULMNA | |
| SCHEMBL3063907 | 0.71 | ALDH1A1 (0.44) | PKMF10PLGPLAUHTR6 | |
| SCHEMBL27489065 | 0.70 | PLG (0.67) | F10PLGPLAUALDH1A1 | |
| Hydrochloric Acid SCHEMBL6793275 | 0.69 | PLG (0.66) | F10PLGPLAU | |
| SCHEMBL6786044 | 0.69 | F10 (0.63) | F10PLGPLAUALDH1A1 | |
| SCHEMBL8721773 | 0.69 | F10 (0.63) | F10PLGPLAUALDH1A1 | |
| SCHEMBL3063905 | 0.68 | ALDH1A1 (0.56) | HTR6LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2905301 | 0.67 | ALDH1A1 (0.48) | PKMF10HTR6LMNAALDH1A1 | |
| SCHEMBL3096727 | 0.67 | F10 (0.51) | F10PLGPLAU | |
| SCHEMBL8278382 | 0.67 | SMN1; SMN2 (0.67) | PKMPLAULMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922313-A1 | PYRAZINE DERIVATIVES USEFUL AS ADENOSINE RECEPTOR ANTAGONISTS | Laboratorios Almirall, S.A. (ES) | 2008-05-21 | — | — | EP | disclosed |
| WO-2007017096-A1 | PYRAZINE DERIVATIVES USEFUL AS ADENOSINE RECEPTOR ANTAGONISTS | LABORATORIOS ALMIRALL, S.A. (ES) | 2007-02-15 | — | — | WO | disclosed |