SCHEMBL4696

SCHEMBL4696

CCCC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 11/20 0.88
SMN1; SMN2 Q16637 3/20 0.88
MAPT P10636 2/20 0.88
POLB P06746 1/20 0.88
GAA P10253 1/20 0.88
NFKB1 P19838 2/20 0.83
PMP22 Q01453 1/20 0.83
TSHR P16473 1/20 0.83
PGR P06401 4/20 0.81
SERPINA6 P08185 2/20 0.81
LMNA P02545 2/20 0.81
AR P10275 2/20 0.81
CHRM1 P11229 2/20 0.81
CYP3A4 P08684 2/20 0.79
NR3C2 P08235 4/20 0.73
NR3C1 P04150 3/20 0.73
CYP2C19 P33261 2/20 0.73
HSD17B10 Q99714 2/20 0.73
KMT2A Q03164 2/20 0.73
SHBG P04278 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2679655 1.00 HIF1A (0.88) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL11252568 1.00 HIF1A (0.88) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL10575587 1.00 HIF1A (0.88) HIF1ASMN1; SMN2MAPTPOLBGAA
Hydrocortisone SCHEMBL365193 0.97 HIF1A (0.83) HIF1ASMN1; SMN2MAPTPOLBGAA
Hydrocortisone Acetate SCHEMBL1535103 0.97 HIF1A (0.87) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL80604 0.96 HIF1A (0.95) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL2679288 0.96 HIF1A (0.95) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL16018308 0.96 HIF1A (0.93) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL5084679 0.94 HIF1A (0.98) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL7137200 0.94 HIF1A (1.00) HIF1ASMN1; SMN2MAPTPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10655 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 US claimed
EP-4744657-A1 THERAPEUTIC AGENT FOR HUMAN GRAFT VERSUS HOST DISEASE AND COMBINATION THEREOF National University Corporation Okayama University (JP) 2026-05-20 EP claimed
US-20260103492-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE BACAINN BIOTHERAPEUTICS, LTD. (KY) 2026-04-16 US claimed
US-20250332120-A1 COMPOSITION FOR EXTERNAL PREPARATION KAO CORPORATION (JP) 2025-10-30 US claimed
US-20250319104-A1 MOISTURIZING CREAM FOR RADIATION DERMATITIS PERRY ARTHUR W (US) 2025-10-16 US claimed
US-12421281-B2 Cyclosporine compositions and methods of use BACAINN BIOTHERAPEUTICS, LTD. (KY) 2025-09-23 US claimed
US-20250288585-A1 SYNERGISTIC COMPOSITIONS FOR ENHANCED HAIR GROWTH AND METHODS FOR TREATING HAIR LOSS THE JOHNS HOPKINS UNIVERSITY 2025-09-18 US claimed
US-20250255781-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-14 US claimed
CN-120189477-A Application of rhizoma polygonati and pharmaceutical composition thereof in preparation of medicines for preventing and treating kidney and liver injury 广东省科学院生物与医学工程研究所 2025-06-24 CN claimed
US-20250179121-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE BACAINN BIOTHERAPEUTICS, LTD. (KY) 2025-06-05 US claimed
EP-0280915-A2 Preparations for topical use of gyrase inhibitors in combination with corticosteroids BAYER AG (DE) 1988-09-07 EP claimed
EP-0241134-A1 Pharmaceutical mixture comprising nedocromil or a salt thereof in combination with a bronchodilator FISONS plc (GB) 1987-10-14 EP claimed
EP-0068553-B1 TOPICAL ANTIMICROBIAL ANTI-INFLAMMATORY COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1985-11-21 EP claimed
US-4473565-A CORTICOSTEROID AND NON-STEROIDAL AGENT JOHNSON & JOHNSON (US) 1984-09-25 US claimed
EP-0068553-A1 Topical antimicrobial anti-inflammatory compositions THE PROCTER & GAMBLE COMPANY (US) 1983-01-05 EP claimed
US-4360518-A MEFENAMIC OR FLUFENAMIC ACID WITH CORTICOSTEROID JOHNSON & JOHNSON (US) 1982-11-23 US claimed
US-4343798-A Topical antimicrobial anti-inflammatory compositions THE PROCTER & GAMBLE COMPANY (US) 1982-08-10 US claimed
US-4282216-A Topical anti-inflammatory drug therapy JOHNSON & JOHNSON (US) 1981-08-04 US claimed
US-4185100-A CORTICOSTEROID AND A HYDROTROPIC ACID DERIVATIVE, ENZYME INHIBITORS JOHNSON & JOHNSON (US) 1980-01-22 US claimed
US-4137311-A CORTICOSTEROIDS, METAL ADDUCTS OF BIS(2-PYRIDYL-1-OXIDE)-DISULFIDE; DERMATITIS, ANTIINFLAMMATORY WILLIAM H. RORER, INC. (US) 1979-01-30 US claimed