Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 11/20 | 0.88 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.88 |
| ▸ | MAPT | P10636 | 2/20 | 0.88 |
| ▸ | POLB | P06746 | 1/20 | 0.88 |
| ▸ | GAA | P10253 | 1/20 | 0.88 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.83 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.83 |
| ▸ | TSHR | P16473 | 1/20 | 0.83 |
| ▸ | PGR | P06401 | 4/20 | 0.81 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | AR | P10275 | 2/20 | 0.81 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.79 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.73 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | SHBG | P04278 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2679655 | 1.00 | HIF1A (0.88) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL11252568 | 1.00 | HIF1A (0.88) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL10575587 | 1.00 | HIF1A (0.88) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| Hydrocortisone Acetate SCHEMBL1535103 | 0.97 | HIF1A (0.87) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| Hydrocortisone SCHEMBL365193 | 0.97 | HIF1A (0.83) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL80604 | 0.96 | HIF1A (0.95) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL2679288 | 0.96 | HIF1A (0.95) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL16018308 | 0.96 | HIF1A (0.93) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL5084679 | 0.94 | HIF1A (0.98) | HIF1ASMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL7137200 | 0.94 | HIF1A (1.00) | HIF1ASMN1; SMN2MAPTPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 10655 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260139030-A1 | CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION | SHATTUCK LABS INC (US) | 2026-05-21 | — | — | US | claimed |
| EP-4744657-A1 | THERAPEUTIC AGENT FOR HUMAN GRAFT VERSUS HOST DISEASE AND COMBINATION THEREOF | National University Corporation Okayama University (JP) | 2026-05-20 | — | — | EP | claimed |
| US-20260103492-A1 | CYCLOSPORINE COMPOSITIONS AND METHODS OF USE | BACAINN BIOTHERAPEUTICS, LTD. (KY) | 2026-04-16 | — | — | US | claimed |
| US-20250332120-A1 | COMPOSITION FOR EXTERNAL PREPARATION | KAO CORPORATION (JP) | 2025-10-30 | — | — | US | claimed |
| US-20250319104-A1 | MOISTURIZING CREAM FOR RADIATION DERMATITIS | PERRY ARTHUR W (US) | 2025-10-16 | — | — | US | claimed |
| US-12421281-B2 | Cyclosporine compositions and methods of use | BACAINN BIOTHERAPEUTICS, LTD. (KY) | 2025-09-23 | — | — | US | claimed |
| US-20250288585-A1 | SYNERGISTIC COMPOSITIONS FOR ENHANCED HAIR GROWTH AND METHODS FOR TREATING HAIR LOSS | THE JOHNS HOPKINS UNIVERSITY | 2025-09-18 | — | — | US | claimed |
| US-20250255781-A1 | PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-08-14 | — | — | US | claimed |
| CN-120189477-A | Application of rhizoma polygonati and pharmaceutical composition thereof in preparation of medicines for preventing and treating kidney and liver injury | 广东省科学院生物与医学工程研究所 | 2025-06-24 | — | — | CN | claimed |
| US-20250179121-A1 | CYCLOSPORINE COMPOSITIONS AND METHODS OF USE | BACAINN BIOTHERAPEUTICS, LTD. (KY) | 2025-06-05 | — | — | US | claimed |
| EP-0280915-A2 | Preparations for topical use of gyrase inhibitors in combination with corticosteroids | BAYER AG (DE) | 1988-09-07 | — | — | EP | claimed |
| EP-0241134-A1 | Pharmaceutical mixture comprising nedocromil or a salt thereof in combination with a bronchodilator | FISONS plc (GB) | 1987-10-14 | — | — | EP | claimed |
| EP-0068553-B1 | TOPICAL ANTIMICROBIAL ANTI-INFLAMMATORY COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1985-11-21 | — | — | EP | claimed |
| US-4473565-A | CORTICOSTEROID AND NON-STEROIDAL AGENT | JOHNSON & JOHNSON (US) | 1984-09-25 | — | — | US | claimed |
| EP-0068553-A1 | Topical antimicrobial anti-inflammatory compositions | THE PROCTER & GAMBLE COMPANY (US) | 1983-01-05 | — | — | EP | claimed |
| US-4360518-A | MEFENAMIC OR FLUFENAMIC ACID WITH CORTICOSTEROID | JOHNSON & JOHNSON (US) | 1982-11-23 | — | — | US | claimed |
| US-4343798-A | Topical antimicrobial anti-inflammatory compositions | THE PROCTER & GAMBLE COMPANY (US) | 1982-08-10 | — | — | US | claimed |
| US-4282216-A | Topical anti-inflammatory drug therapy | JOHNSON & JOHNSON (US) | 1981-08-04 | — | — | US | claimed |
| US-4185100-A | CORTICOSTEROID AND A HYDROTROPIC ACID DERIVATIVE, ENZYME INHIBITORS | JOHNSON & JOHNSON (US) | 1980-01-22 | — | — | US | claimed |
| US-4137311-A | CORTICOSTEROIDS, METAL ADDUCTS OF BIS(2-PYRIDYL-1-OXIDE)-DISULFIDE; DERMATITIS, ANTIINFLAMMATORY | WILLIAM H. RORER, INC. (US) | 1979-01-30 | — | — | US | claimed |