SCHEMBL80604

SCHEMBL80604

CCCCC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 11/20 0.95
SMN1; SMN2 Q16637 3/20 0.95
MAPT P10636 2/20 0.95
POLB P06746 1/20 0.95
GAA P10253 1/20 0.95
NFKB1 P19838 2/20 0.82
PMP22 Q01453 1/20 0.82
TSHR P16473 1/20 0.82
PGR P06401 4/20 0.80
SERPINA6 P08185 2/20 0.80
LMNA P02545 2/20 0.80
AR P10275 2/20 0.80
CHRM1 P11229 2/20 0.80
CYP3A4 P08684 2/20 0.78
NR3C2 P08235 4/20 0.72
NR3C1 P04150 3/20 0.72
CYP2C19 P33261 2/20 0.72
HSD17B10 Q99714 2/20 0.72
KMT2A Q03164 2/20 0.72
SHBG P04278 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2679288 1.00 HIF1A (0.95) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL5084679 0.98 HIF1A (0.98) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL7142712 0.98 HIF1A (1.00) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL141851 0.98 HIF1A (1.00) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL7137200 0.98 HIF1A (1.00) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL3488312 0.98 HIF1A (1.00) HIF1ASMN1; SMN2MAPTPOLBGAA
Hydrocortisone SCHEMBL365890 0.97 HIF1A (0.90) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL10575587 0.96 HIF1A (0.88) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL2679655 0.96 HIF1A (0.88) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL4696 0.96 HIF1A (0.88) HIF1ASMN1; SMN2MAPTPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7437 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103492-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE BACAINN BIOTHERAPEUTICS, LTD. (KY) 2026-04-16 US claimed
US-12421281-B2 Cyclosporine compositions and methods of use BACAINN BIOTHERAPEUTICS, LTD. (KY) 2025-09-23 US claimed
US-20250288585-A1 SYNERGISTIC COMPOSITIONS FOR ENHANCED HAIR GROWTH AND METHODS FOR TREATING HAIR LOSS THE JOHNS HOPKINS UNIVERSITY 2025-09-18 US claimed
US-20250179121-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE BACAINN BIOTHERAPEUTICS, LTD. (KY) 2025-06-05 US claimed
WO-2025090570-A1 ANTI-OX40L ANTIBODIES AND METHODS OF USE ABCELLERA BIOLOGICS INC. (CA) 2025-05-01 WO claimed
WO-2025085674-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF ULCERATIVE COLITIS BACAINN THERAPEUTICS, INC. (US) 2025-04-24 WO claimed
US-20250099498-A1 STRONTIUM BASED COMPOSITIONS AND FORMULATIONS FOR PAIN, PRURITUS, AND INFLAMMATION GALLEON LABS LLC (US) 2025-03-27 US claimed
US-12252556-B2 Cyclosporine compositions and methods of use BACAINN BIOTHERAPEUTICS, LTD. (KY) 2025-03-18 US claimed
US-20250025479-A1 TRANSPORE DELIVERY OF STEROIDS AND LARGE MOLECULES STUDIN JOEL (US) 2025-01-23 US claimed
EP-4475851-A1 FORMULATIONS FOR TRANSDERMAL ADMINISTRATION OF ACTIVE AGENTS Dyve Biosciences, Inc. (US) 2024-12-18 EP claimed
US-5215965-A Administering corticosteroid and at least one serine protease inhibitor, its salt or derivatives which bind with the mediators of mast or T-cells SONORAN DESERT CHEMICALS CORP. LLC 1993-06-01 US claimed
US-5190917-A Mast cell and T-cell inhibitor LEZDEY, JARETT 1993-03-02 US claimed
US-5061700-A SOLVENTS FOR CORTICOSTEROIDS Dow, Gordon Jay (US) 1991-10-29 US claimed
WO-1991007169-A1 GLYCERYL ACETATE OINTMENT VEHICLES DOW GORDON JAY (US) 1991-05-30 WO claimed
US-4992478-A Antiinflammatory skin moisturizing composition and method of preparing same WARNER-LAMBERT COMPANY (US) 1991-02-12 US claimed
EP-0391033-A2 Retinal, derivatives and their therapeutic use Yu, Ruey J., Dr. (US) 1990-10-10 EP claimed
EP-0336902-A2 Antiinflammatory skin moisturizing composition and method of preparing same WARNER-LAMBERT COMPANY (US) 1989-10-11 EP claimed
US-4797402-A CORTICOSTEROIDS, PEPPERMINT, UREA DORSEY KENNETH E (US) 1989-01-10 US claimed
US-4244942-A Creamy preparation containing steroid and process for the preparation thereof TOKO YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1981-01-13 US claimed
US-4137311-A CORTICOSTEROIDS, METAL ADDUCTS OF BIS(2-PYRIDYL-1-OXIDE)-DISULFIDE; DERMATITIS, ANTIINFLAMMATORY WILLIAM H. RORER, INC. (US) 1979-01-30 US claimed