Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696207 | 1.00 | KDM4E (0.38) | KDM4ETSHRATMLMNAALDH1A1 | |
| SCHEMBL910009 | 0.81 | KDM4E (0.52) | KDM4ETSHRLMNA | |
| SCHEMBL4640514 | 0.81 | KDM4E (0.52) | KDM4ETSHRLMNA | |
| SCHEMBL910007 | 0.81 | KDM4E (0.52) | KDM4ETSHRLMNA | |
| SCHEMBL13569511 | 0.76 | — | — | |
| SCHEMBL8980050 | 0.76 | — | — | |
| SCHEMBL8980049 | 0.76 | — | — | |
| SCHEMBL9298720 | 0.75 | KDM4E (0.38) | KDM4ETSHR | |
| SCHEMBL9298721 | 0.75 | KDM4E (0.38) | KDM4ETSHR | |
| SCHEMBL6047074 | 0.74 | KDM4E (0.35) | KDM4ETSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294705-B1 | SYNTHESIS OF CYCLIC COMPOUNDS | BIOSIGNAL LTD (AU) | 2008-09-10 | — | — | EP | disclosed |
| US-6958145-B2 | Synthesis of cyclic compounds | UNISEARCH LIMITED (AU) | 2005-10-25 | — | — | US | disclosed |
| EP-1294705-A4 | SYNTHESIS OF CYCLIC COMPOUNDS | UNISEARCH LTD (AU) | 2005-02-09 | — | — | EP | disclosed |
| US-20040110966-A1 | Synthesis of cyclic compounds | UNISEARCH LIMITED (AU) | 2004-06-10 | — | — | US | disclosed |
| EP-1294705-A1 | SYNTHESIS OF CYCLIC COMPOUNDS | UNISEARCH LIMITED (AU) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000639-A1 | SYNTHESIS OF CYCLIC COMPOUNDS | UNISEARCH LIMITED (AU) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110966-A1 | Synthesis of cyclic compounds | RFC2, POLR2H, REV1 | KDM4E 3671/4885TSHR 684/4885ATM 3950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.