Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699749 | 0.96 | CCR5 (0.73) | CCR5 | |
| SCHEMBL4699750 | 0.96 | CCR5 (0.73) | CCR5 | |
| SCHEMBL4697063 | 0.86 | CCR5 (0.71) | CCR5 | |
| SCHEMBL4696732 | 0.86 | CCR5 (0.71) | CCR5 | |
| SCHEMBL4696728 | 0.86 | CCR5 (0.71) | CCR5 | |
| SCHEMBL4696894 | 0.85 | CCR5 (0.75) | CCR5 | |
| SCHEMBL4696896 | 0.85 | CCR5 (0.75) | CCR5 | |
| SCHEMBL3289105 | 0.85 | CCR5 (0.77) | CCR5 | |
| SCHEMBL3289096 | 0.85 | CCR5 (0.77) | CCR5 | |
| SCHEMBL4697080 | 0.85 | CCR5 (0.71) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987036-A1 | HETERO-BYCYCLIC ANTIVIRAL COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093520-A1 | HETERO-BYCYCLIC ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-23 | — | — | WO | disclosed |