Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699937 | 0.88 | — | — | |
| SCHEMBL1448754 | 0.77 | — | — | |
| SCHEMBL4700152 | 0.76 | PDE1A (0.33) | — | |
| SCHEMBL1447305 | 0.73 | HTT (0.38) | HTT | |
| SCHEMBL1449077 | 0.70 | HTT (0.37) | HTT | |
| SCHEMBL1555035 | 0.61 | P2RX7 (0.35) | — | |
| SCHEMBL25028002 | 0.61 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL4713935 | 0.60 | KDM4E (0.43) | — | |
| SCHEMBL1652097 | 0.59 | HDAC1 (0.44) | — | |
| SCHEMBL19368026 | 0.59 | SMN1; SMN2 (0.35) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912974-A1 | IMIDAZOLYL-PYRIMIDINE COMPOUNDS FOR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | AstraZeneca AB (SE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007015064-A1 | IMIDAZOLYL-PYRIMIDINE COMPOUNDS FOR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2007-02-08 | — | — | WO | disclosed |