Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465338 | 0.85 | CNR1 (0.57) | CNR1ALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL4695651 | 0.84 | CNR1 (0.60) | CNR1ALDH1A1POLBHPGDRAB9A | |
| SCHEMBL4459567 | 0.75 | ALDH1A1 (0.68) | CNR1ALDH1A1POLBHPGDRAB9A | |
| SCHEMBL4465606 | 0.73 | CNR1 (0.97) | CNR1ALDH1A1HPGDRECQLHSD17B10 | |
| SCHEMBL4469473 | 0.72 | CNR1 (1.00) | CNR1ALDH1A1HPGDRECQLHSD17B10 | |
| SCHEMBL4463145 | 0.70 | CNR1 (0.77) | CNR1ALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL4465410 | 0.69 | CNR1 (0.71) | CNR1ALDH1A1HPGDSRD5A1SRD5A2 | |
| SCHEMBL4465268 | 0.69 | CNR1 (0.70) | CNR1ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL4465277 | 0.68 | CNR1 (0.77) | CNR1ALDH1A1POLBHPGDMAPT | |
| SCHEMBL4461776 | 0.68 | CNR1 (0.69) | CNR1ALDH1A1L3MBTL1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532132-B1 | NOVEL BENZODIOXOLES | HOFFMANN LA ROCHE (CH) | 2008-03-19 | — | — | EP | claimed |