Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.46 |
| ▸ | CA2 | P00918 | 11/20 | 0.46 |
| ▸ | CA12 | O43570 | 10/20 | 0.46 |
| ▸ | CA9 | Q16790 | 9/20 | 0.46 |
| ▸ | CA4 | P22748 | 8/20 | 0.46 |
| ▸ | CA6 | P23280 | 8/20 | 0.46 |
| ▸ | CA7 | P43166 | 8/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 7/20 | 0.46 |
| ▸ | CA5A | P35218 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 5/20 | 0.37 |
| ▸ | AQP1 | P29972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697411 | 0.88 | CA1 (0.45) | CA1CA2CA12CA9CA4 | |
| SCHEMBL1743054 | 0.85 | CA12 (0.50) | CA1CA2CA12CA9CA4 | |
| SCHEMBL2959177 | 0.82 | CA12 (0.67) | CA1CA2CA12CA9CA4 | |
| SCHEMBL1741237 | 0.78 | CA1 (0.52) | CA1CA2CA12CA9CA4 | |
| SCHEMBL2959448 | 0.76 | CA12 (0.65) | CA1CA2CA12CA9CA4 | |
| SCHEMBL2956662 | 0.76 | CA12 (0.65) | CA1CA2CA12CA9CA4 | |
| SCHEMBL2947218 | 0.75 | CA12 (0.72) | CA1CA2CA12CA9CA4 | |
| SCHEMBL8295407 | 0.72 | CA12 (0.64) | CA1CA2CA12CA9CA4 | |
| SCHEMBL2957873 | 0.71 | CA12 (0.66) | CA1CA2CA12CA9CA4 | |
| SCHEMBL2956412 | 0.71 | CISD1 (0.65) | CA1CA2CA12CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968603-A2 | THERAPEUTIC AMINE-ARYLSULFONAMIDE CONJUGATE COMPOUNDS | Algebra Inc. (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007079470-A2 | THERAPEUTIC AMINE-ARYLSULFONAMIDE CONJUGATE COMPOUNDS | ALGEBRA, INC. (US) | 2007-07-12 | — | — | WO | disclosed |