Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.45 |
| ▸ | CA2 | P00918 | 8/20 | 0.45 |
| ▸ | CA9 | Q16790 | 8/20 | 0.45 |
| ▸ | CA12 | O43570 | 7/20 | 0.45 |
| ▸ | CA6 | P23280 | 6/20 | 0.45 |
| ▸ | CA7 | P43166 | 6/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.45 |
| ▸ | CA5A | P35218 | 5/20 | 0.45 |
| ▸ | CA4 | P22748 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697409 | 0.88 | CA1 (0.46) | CA1CA2CA9CA12CA6 | |
| SCHEMBL1743054 | 0.84 | CA12 (0.50) | CA1CA2CA9CA12CA6 | |
| SCHEMBL2959179 | 0.83 | CA12 (0.66) | CA1CA2CA9CA12CA6 | |
| SCHEMBL1741237 | 0.77 | CA1 (0.52) | CA1CA2CA9CA12CA6 | |
| SCHEMBL2956665 | 0.77 | CA12 (0.65) | CA1CA2CA9CA12CA6 | |
| SCHEMBL2959449 | 0.74 | CA12 (0.61) | CA1CA2CA9CA12CA6 | |
| SCHEMBL2947218 | 0.71 | CA12 (0.72) | CA1CA2CA9CA12CA6 | |
| SCHEMBL2959177 | 0.70 | CA12 (0.67) | CA1CA2CA9CA12CA6 | |
| SCHEMBL2960965 | 0.69 | CA12 (0.69) | CA1CA2CA9CA12CA6 | |
| SCHEMBL229100 | 0.69 | CA12 (0.68) | CA1CA2CA9CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968603-A2 | THERAPEUTIC AMINE-ARYLSULFONAMIDE CONJUGATE COMPOUNDS | Algebra Inc. (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007079470-A2 | THERAPEUTIC AMINE-ARYLSULFONAMIDE CONJUGATE COMPOUNDS | ALGEBRA, INC. (US) | 2007-07-12 | — | — | WO | disclosed |