Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CALML3 | P27482 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 3/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412056 | 0.89 | CALML3 (0.43) | F10CYP2C19CYP2C9MAOBCYP3A4 | |
| SCHEMBL412968 | 0.87 | MAOA (0.37) | CYP2C19CYP2C9MAOBCYP3A4MAOA | |
| SCHEMBL463275 | 0.86 | F10 (0.40) | F10MAOBMAOACALML3CETP | |
| SCHEMBL412683 | 0.75 | MAOA (0.44) | F10CYP2C19CYP2C9MAOBCYP3A4 | |
| SCHEMBL412177 | 0.74 | CNR2 (0.45) | F10CYP2C19CYP2C9MAOBCYP3A4 | |
| SCHEMBL412753 | 0.74 | CALML3 (0.48) | CYP2C19CYP2C9MAOBCYP3A4MAOA | |
| SCHEMBL412048 | 0.74 | MAOA (0.44) | CYP2C19CYP2C9MAOBCYP3A4MAOA | |
| SCHEMBL411141 | 0.74 | CALML3 (0.64) | CYP2C19CYP2C9MAOBCYP3A4MAOA | |
| SCHEMBL463353 | 0.74 | F10 (0.44) | F10MAOBMAOACALML3CETP | |
| SCHEMBL412043 | 0.74 | CALML3 (0.48) | F10CYP2C19CYP2C9MAOBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033952-A1 | 3 - PHENYL- 2 -OXO- 1, 3 -OXAZOLIDINES FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (KY) | 2012-03-15 | — | — | WO | disclosed |