Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697713 | 1.00 | MAPT (0.51) | MAPTPOLBLMNAKDM4EHPGD | |
| SCHEMBL4697823 | 0.93 | MAPT (0.48) | MAPTPOLBLMNAKDM4EHPGD | |
| SCHEMBL398853 | 0.93 | MAPT (0.48) | MAPTPOLBLMNAKDM4EHPGD | |
| SCHEMBL398854 | 0.93 | MAPT (0.48) | MAPTPOLBLMNAKDM4EHPGD | |
| SCHEMBL4697819 | 0.93 | MAPT (0.48) | MAPTPOLBLMNAKDM4EHPGD | |
| SCHEMBL530029 | 0.89 | MAPT (0.55) | MAPTPOLBLMNAKDM4EHPGD | |
| SCHEMBL529833 | 0.89 | MAPT (0.55) | MAPTPOLBLMNAKDM4EHPGD | |
| SCHEMBL4699454 | 0.88 | LMNA (0.44) | MAPTPOLBLMNAKDM4EHPGD | |
| SCHEMBL4699456 | 0.88 | LMNA (0.44) | MAPTPOLBLMNAKDM4EHPGD | |
| SCHEMBL915015 | 0.88 | MAPT (0.55) | MAPTPOLBLMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | claimed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |