Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 15/20 | 0.44 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4676307 | 0.99 | MC4R (0.43) | MC4RAKT1TACR1DPP4 | |
| SCHEMBL4700176 | 0.81 | MAPK1 (0.45) | TACR1 | |
| SCHEMBL4703607 | 0.80 | MC4R (0.47) | MC4RTACR1 | |
| Hydrochloric Acid SCHEMBL4676306 | 0.78 | AKT1 (0.41) | MC4RAKT1DPP4 | |
| SCHEMBL4701631 | 0.77 | BRD4 (0.43) | MC4R | |
| SCHEMBL6254758 | 0.74 | TACR1 (0.55) | MC4RAKT1TACR1DPP4 | |
| SCHEMBL4676043 | 0.74 | TACR1 (0.55) | MC4RAKT1TACR1DPP4 | |
| SCHEMBL4697732 | 0.74 | MC4R (0.36) | MC4R | |
| Hydrochloric Acid SCHEMBL4702657 | 0.74 | MC4R (0.36) | MC4R | |
| SCHEMBL4702527 | 0.74 | MAOB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416933-B1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM INC (US) | 2008-01-02 | — | — | EP | disclosed |