Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 4/20 | 0.34 |
| ▸ | MMP9 | P14780 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4702657 | 0.99 | MC4R (0.36) | MC4RTDP1MMP2MMP9 | |
| SCHEMBL4697730 | 0.74 | MC4R (0.44) | MC4R | |
| Hydrochloric Acid SCHEMBL4676307 | 0.74 | MC4R (0.43) | MC4R | |
| SCHEMBL4702527 | 0.66 | MAOB (0.38) | — | |
| Hydrochloric Acid SCHEMBL4698894 | 0.65 | HTR2C (0.39) | — | |
| SCHEMBL5478550 | 0.62 | MC4R (0.59) | MC4R | |
| SCHEMBL4700176 | 0.60 | MAPK1 (0.45) | TDP1 | |
| SCHEMBL12346685 | 0.60 | MEN1 (0.42) | TDP1 | |
| SCHEMBL1529828 | 0.58 | SLC6A4 (0.53) | TDP1MMP2MMP9 | |
| SCHEMBL1529830 | 0.58 | SLC6A4 (0.53) | TDP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416933-B1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM INC (US) | 2008-01-02 | — | — | EP | disclosed |