⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2398119 | 0.64 | — | — | |
| SCHEMBL5800226 | 0.58 | KDM4E (0.42) | — | |
| SCHEMBL5799348 | 0.58 | KDM4E (0.39) | — | |
| SCHEMBL14889375 | 0.51 | — | — | |
| SCHEMBL9578382 | 0.50 | — | — | |
| SCHEMBL1004526 | 0.45 | — | — | |
| SCHEMBL186926 | 0.45 | — | — | |
| SCHEMBL10793630 | 0.41 | — | — | |
| SCHEMBL4727307 | 0.39 | — | — | |
| SCHEMBL724 | 0.25 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973920-A2 | PROCESS FOR THE PREPARATION OF 5-AMINO-3H-THIAZOLO [4,5-D] PYRIMIDIN-2-ONE | Anadys Pharmaceuticals, Inc. (US) | 2008-10-01 | — | — | EP | claimed |
| WO-2007062355-A2 | PROCESS FOR THE PREPARATION OF 5-AMINO-3H- THIAZOLO [4 , 5 -d] PYRIMIDIN- 2 -ONE | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-31 | — | — | WO | claimed |
| WO-2025229177-A1 | CRYSTALLINE FORMS OF AN N-SUBSTITUTED INDOLE DERIVATIVE | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-11-06 | — | — | WO | disclosed |
| EP-3625224-B1 | N-SUBSTITUTED INDOLE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-08-04 | — | — | EP | disclosed |
| EP-1661896-A1 | PYRROLOPYRIMIDINETHIONE DERIVATIVE | Teijin Pharma Limited (JP) | 2006-05-31 | — | — | EP | disclosed |
| US-20050153992-A1 | Pyrrolopyrimidine thion derivatives | TEIJIN PHARMA LIMITED (JP) | 2005-07-14 | — | — | US | disclosed |