Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27727530 | 0.92 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL4650759 | 0.88 | KMT2A (0.51) | ALDH1A1SMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL4650555 | 0.84 | KDM4E (0.59) | ALDH1A1SMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL4650513 | 0.84 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL29193536 | 0.82 | KMT2A (0.59) | ALDH1A1SMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL4650471 | 0.81 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL4650312 | 0.81 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL4651062 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL4697515 | 0.79 | HCAR2 (0.58) | ALDH1A1SMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL111479 | 0.78 | KMT2A (0.70) | ALDH1A1SMN1; SMN2LMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966181-A2 | ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS | Wyeth (US) | 2008-09-10 | — | — | EP | claimed |
| WO-2008051244-A2 | ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS | WYETH (US) | 2008-05-02 | — | — | WO | claimed |