Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28728217 | 0.82 | — | — | |
| SCHEMBL30629416 | 0.78 | NFKB1 (0.37) | FDPSLMNA | |
| SCHEMBL22249 | 0.78 | — | — | |
| SCHEMBL6440574 | 0.77 | — | — | |
| SCHEMBL28728299 | 0.77 | — | — | |
| SCHEMBL27846777 | 0.77 | — | — | |
| SCHEMBL11621044 | 0.76 | FFAR1 (0.38) | FDPS | |
| SCHEMBL19263940 | 0.75 | — | — | |
| SCHEMBL6138531 | 0.75 | — | — | |
| SCHEMBL15115418 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001885-A2 | OCTAHYDRO-PYRROLO[3,4-B]PYRROLE DERIVATIVES | Abbott Laboratories (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007100990-A2 | OCTAHYDRO-PYRROLO[3,4-B] PYRROLE DERIVATIVES AND THEIR USE AS HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2007-09-07 | — | — | WO | disclosed |