SCHEMBL4698308

SCHEMBL4698308

CCCC(OC(C)=O)OC(=O)C(N)C1CCC(C(=O)O)CC1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.33
ENPEP Q07075 1/20 0.33
PLG P00747 1/20 0.32
PLAT P00750 1/20 0.32
LMNA P02545 1/20 0.32
GPR88 Q9GZN0 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL915841 1.00 ANPEP (0.33) ANPEPENPEPPLGPLATLMNA
SCHEMBL4700722 0.91 ANPEP (0.33) ANPEPENPEPPLGPLATLMNA
SCHEMBL916297 0.91 ANPEP (0.33) ANPEPENPEPPLGPLATLMNA
SCHEMBL4698912 0.90 ANPEP (0.33) ANPEPENPEPPLGPLATLMNA
SCHEMBL915023 0.90 ANPEP (0.33) ANPEPENPEPPLGPLATLMNA
SCHEMBL2973374 0.87 ANPEP (0.31) ANPEPENPEPPLGPLATLMNA
SCHEMBL8222633 0.87 ANPEP (0.31) ANPEPENPEPPLGPLATLMNA
SCHEMBL916756 0.86 MMP1 (0.33) ANPEPENPEP
SCHEMBL8222755 0.86 KMT2A (0.31) ANPEPENPEP
SCHEMBL915179 0.86 KMT2A (0.31) ANPEPENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1919859-A2 ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE Xenoport, Inc. (US) 2008-05-14 EP disclosed
WO-2007002013-A2 ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE XENOPORT, INC. (US) 2007-01-04 WO disclosed