Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916672 | 1.00 | DPP4 (0.37) | DPP4DPP7KCNH2ANPEPENPEP | |
| SCHEMBL916106 | 0.85 | DPP4 (0.33) | DPP4DPP7KCNH2ANPEPENPEP | |
| SCHEMBL8216296 | 0.85 | DPP4 (0.33) | DPP4DPP7KCNH2ANPEPENPEP | |
| SCHEMBL915152 | 0.84 | ANPEP (0.35) | ANPEPENPEP | |
| SCHEMBL915150 | 0.84 | ANPEP (0.35) | ANPEPENPEP | |
| SCHEMBL4699309 | 0.81 | ANPEP (0.33) | ANPEPENPEP | |
| SCHEMBL914976 | 0.81 | ANPEP (0.33) | ANPEPENPEP | |
| SCHEMBL916188 | 0.79 | ANPEP (0.35) | ANPEPENPEP | |
| SCHEMBL3256826 | 0.79 | ANPEP (0.35) | ANPEPENPEP | |
| Acetic Acid SCHEMBL614056 | 0.78 | DPP4 (0.40) | DPP4DPP7KCNH2EPHX1DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |