Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916106 | 1.00 | DPP4 (0.33) | DPP4LMNAKCNH2DPP7ANPEP | |
| SCHEMBL916672 | 0.85 | DPP4 (0.37) | DPP4KCNH2DPP7ANPEPENPEP | |
| SCHEMBL4698314 | 0.85 | DPP4 (0.37) | DPP4KCNH2DPP7ANPEPENPEP | |
| SCHEMBL915707 | 0.84 | LMNA (0.33) | LMNAANPEPENPEPALDH1A1 | |
| SCHEMBL4700619 | 0.84 | LMNA (0.33) | LMNAANPEPENPEPALDH1A1 | |
| SCHEMBL4699450 | 0.83 | ANPEP (0.33) | LMNAANPEPENPEPALDH1A1 | |
| SCHEMBL914994 | 0.83 | ANPEP (0.33) | LMNAANPEPENPEPALDH1A1 | |
| SCHEMBL914979 | 0.81 | ANPEP (0.32) | LMNAANPEPENPEPALDH1A1 | |
| SCHEMBL4700077 | 0.81 | ANPEP (0.32) | LMNAANPEPENPEPALDH1A1 | |
| SCHEMBL8222633 | 0.81 | ANPEP (0.31) | LMNAANPEPENPEPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011028234-A1 | USES OF ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID | XENOPORT, INC. (US) | 2011-03-10 | — | — | WO | disclosed |