Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1453522 | 0.92 | TOP1 (0.35) | TOP1 | |
| SCHEMBL1452427 | 0.85 | TOP1 (0.35) | TOP1 | |
| SCHEMBL1451702 | 0.79 | GABRA1 (0.31) | — | |
| SCHEMBL1453718 | 0.79 | TOP1 (0.38) | TOP1 | |
| SCHEMBL1451774 | 0.77 | PBRM1 (0.32) | — | |
| SCHEMBL1452585 | 0.75 | TOP1 (0.30) | TOP1 | |
| SCHEMBL1453022 | 0.75 | DRD1 (0.33) | TOP1 | |
| SCHEMBL1452233 | 0.72 | HTR2A (0.37) | — | |
| SCHEMBL1453017 | 0.72 | HTR2A (0.32) | — | |
| SCHEMBL1454523 | 0.72 | TOP1 (0.38) | TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971621-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | ExxonMobil Chemical Patents Inc. (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007070045-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |