Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698396 | 0.89 | GRIN2D (0.58) | MAPTKMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL4698608 | 0.80 | MAPT (0.54) | MAPTKMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL4699427 | 0.79 | GRIN2D (0.68) | MAPTKMT2ARAB9AMEN1CHIA | |
| SCHEMBL7748696 | 0.79 | MAPT (0.55) | MAPTKMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL31105723 | 0.79 | MAPT (0.55) | MAPTKMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL21538104 | 0.79 | KMT2A (0.64) | MAPTKMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL7748700 | 0.79 | MAPT (0.55) | MAPTKMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL28884203 | 0.79 | GAA (0.68) | MAPTKMT2ARAB9AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7747578 | 0.78 | MAPT (0.54) | MAPTKMT2ARAB9AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21519408 | 0.78 | KMT2A (0.63) | MAPTKMT2ARAB9AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | claimed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |