Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 2/20 | 0.40 |
| ▸ | LDHB | P07195 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17874283 | 0.85 | MAPK1 (0.52) | SMN1; SMN2ALDH1A1MAPK1POLBCYP3A4 | |
| SCHEMBL10864783 | 0.83 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPK1POLBCYP3A4 | |
| SCHEMBL7788152 | 0.81 | ALDH1A1 (0.68) | SMN1; SMN2ALDH1A1MAPK1POLBCYP3A4 | |
| SCHEMBL31125623 | 0.81 | ALDH1A1 (0.68) | SMN1; SMN2ALDH1A1MAPK1POLBCYP3A4 | |
| SCHEMBL11732815 | 0.79 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1MAPK1POLBCYP3A4 | |
| SCHEMBL29898229 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1MAPK1POLBCYP3A4 | |
| SCHEMBL3340047 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1MAPK1POLBCYP3A4 | |
| SCHEMBL3986248 | 0.78 | ALDH1A1 (0.63) | SMN1; SMN2ALDH1A1MAPK1POLBCYP3A4 | |
| Hydrochloric Acid SCHEMBL920573 | 0.76 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1MAPK1POLBCYP3A4 | |
| SCHEMBL31214299 | 0.76 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1MAPK1POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486489-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2016-04-27 | — | — | EP | disclosed |
| EP-1516874-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2015-08-19 | — | — | EP | disclosed |
| EP-1204643-B1 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | DOW AGROSCIENCES LLC (US) | 2008-06-04 | — | — | EP | disclosed |
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-7034035-B2 | Fungicidal mono-, bi-, and tri-cycloheteroalkyl amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2006-04-25 | — | — | US | disclosed |
| US-6927225-B2 | Fungicidal 2-pyridyl alkyl amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2005-08-09 | — | — | US | disclosed |
| EP-1516875-A1 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | Dow AgroSciences LLC (US) | 2005-03-23 | — | — | EP | disclosed |
| EP-1516874-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2005-03-23 | — | — | EP | disclosed |
| EP-1493733-A2 | Fungicidal heterocyclic aromatic amides, their compositions and methods of use | Dow AgroSciences LLC (US) | 2005-01-05 | — | — | EP | disclosed |
| EP-1486489-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2004-12-15 | — | — | EP | disclosed |
| US-6355660-B1 | HETEROCYCLIC FUNGICIDES SUBSTITUTED WITH AMIDE GROUPS | DOW AGROSCIENCES LLC | 2002-03-12 | — | — | US | disclosed |
| WO-2001014339-A2 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | DOW AGROSCIENCES LLC (US) | 2001-03-01 | — | — | WO | disclosed |
| WO-2001005769-A2 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | DOW AGROSCIENCES LLC (US) | 2001-01-25 | — | — | WO | disclosed |
| EP-0835109-A4 | PYRIDINONE-THROMBIN INHIBITORS | MERCK & CO INC (US) | 1999-02-03 | — | — | EP | disclosed |
| US-5744486-A | Pyridinone thrombin inhibitors | MERCK & CO., INC. (US) | 1998-04-28 | — | — | US | disclosed |
| EP-0835109-A1 | PYRIDINONE-THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 1998-04-15 | — | — | EP | disclosed |
| US-5668289-A | Pyridinone thrombin inhibitors | MERCK & CO., INC. (US) | 1997-09-16 | — | — | US | disclosed |
| WO-1997001338-A1 | PYRIDINONE-THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 1997-01-16 | — | — | WO | disclosed |
| EP-0351399-A1 | ISOQUINOLINE DERIVATIVES, THEIR MANUFACTURE AND USE | HUHTAMÄKI OY (FI) | 1990-01-24 | — | — | EP | disclosed |
| WO-1988007041-A1 | ISOQUINOLINE DERIVATIVES, THEIR MANUFACTURE AND USE | Huhtamäki Oy (FI) | 1988-09-22 | — | — | WO | disclosed |