Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699428 | 0.89 | PTGES (0.60) | PTGESPPARGPPARA | |
| SCHEMBL4021254 | 0.87 | PTGES (0.59) | PTGESSMN1; SMN2THRBPPARGPPARA | |
| SCHEMBL3012072 | 0.86 | PTGES (0.51) | PTGESSMN1; SMN2THRBPPARGPPARA | |
| SCHEMBL4698398 | 0.86 | PTGES (0.55) | PTGESSMN1; SMN2THRBPPARGPPARA | |
| SCHEMBL4924260 | 0.86 | KMT2A (0.48) | PTGESSMN1; SMN2THRBMEN1KMT2A | |
| SCHEMBL4700284 | 0.85 | PTGES (0.37) | PTGESSMN1; SMN2THRBPPARGPPARA | |
| SCHEMBL4700726 | 0.84 | PTGES (0.53) | PTGESSMN1; SMN2THRBPPARGPPARA | |
| SCHEMBL334136 | 0.84 | PTGES (0.53) | PTGESSMN1; SMN2THRBPPARGPPARA | |
| SCHEMBL4698605 | 0.83 | PTGES (0.50) | PTGESSMN1; SMN2THRBPPARGPPARA | |
| SCHEMBL4700108 | 0.83 | PTGES (0.51) | PTGESSMN1; SMN2THRBPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778633-B1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2008-12-03 | — | — | EP | disclosed |
| US-20080188473-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188473-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, PTGS1, PTGER1 | PTGES 4/4885SMN1; SMN2 4126/4885THRB 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.