Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.52 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | IAPP | P10997 | 1/20 | 0.50 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469923 | 0.84 | FFAR1 (0.69) | LMNAL3MBTL1SLC5A1SLC5A2FFAR1 | |
| SCHEMBL26638196 | 0.84 | FFAR1 (0.59) | LMNAL3MBTL1SLC5A1SLC5A2FFAR1 | |
| SCHEMBL12000868 | 0.81 | CYP4F2 (0.64) | LMNAL3MBTL1SLC5A1SLC5A2FFAR1 | |
| SCHEMBL1295644 | 0.81 | SLC5A1 (0.55) | LMNAL3MBTL1SLC5A1SLC5A2FFAR1 | |
| SCHEMBL10138384 | 0.80 | PLK1 (0.51) | LMNAL3MBTL1SLC5A1SLC5A2FFAR1 | |
| SCHEMBL10613369 | 0.79 | NQO1 (0.58) | L3MBTL1FFAR1FFAR4MAPTTHRB | |
| SCHEMBL17614864 | 0.79 | NQO1 (0.58) | L3MBTL1FFAR1FFAR4MAPTTHRB | |
| SCHEMBL26638128 | 0.79 | SLC5A1 (0.50) | LMNAL3MBTL1SLC5A1SLC5A2FFAR1 | |
| SCHEMBL8819093 | 0.78 | SLC5A1 (0.59) | LMNAL3MBTL1SLC5A1SLC5A2FFAR1 | |
| SCHEMBL1205605 | 0.78 | LMNA (0.75) | LMNAL3MBTL1SLC5A1SLC5A2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032014-A1 | ETHYNE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-03-15 | — | — | WO | disclosed |