Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 19/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701031 | 0.93 | OPRM1 (0.76) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL4754480 | 0.87 | OPRM1 (0.86) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL6023239 | 0.86 | OPRM1 (0.81) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL4700444 | 0.83 | OPRM1 (0.85) | OPRM1KCNH2OPRD1OPRK1 | |
| Cp-866087 SCHEMBL14161503 | 0.80 | OPRM1 (1.00) | OPRM1KCNH2OPRD1OPRK1 | |
| Cp-866087 SCHEMBL16292952 | 0.80 | OPRM1 (1.00) | OPRM1KCNH2OPRD1OPRK1 | |
| Cp-866087 SCHEMBL4697312 | 0.80 | OPRM1 (1.00) | OPRM1KCNH2OPRD1OPRK1 | |
| Cp-866087 SCHEMBL18091510 | 0.79 | OPRM1 (0.98) | OPRM1KCNH2OPRD1OPRK1 | |
| Cp-866087 SCHEMBL4700040 | 0.79 | OPRM1 (0.98) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL18091551 | 0.77 | OPRM1 (1.00) | OPRM1KCNH2OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440059-B1 | 3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES AS OPIOID RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2008-04-16 | — | — | EP | claimed |