Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625299 | 0.76 | — | — | |
| SCHEMBL1627388 | 0.76 | — | — | |
| SCHEMBL7759973 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHRKMT2ASMN1; SMN2MAPT | |
| SCHEMBL28111484 | 0.74 | — | — | |
| SCHEMBL4556976 | 0.74 | — | — | |
| SCHEMBL1389030 | 0.73 | TSHR (0.40) | ALDH1A1TSHRKMT2ASMN1; SMN2MAPT | |
| SCHEMBL4698983 | 0.73 | TSHR (0.40) | ALDH1A1TSHRKMT2ASMN1; SMN2MAPT | |
| SCHEMBL906226 | 0.73 | ALDH1A1 (0.40) | ALDH1A1TSHRKMT2ASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL11803255 | 0.71 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL11803259 | 0.71 | ALDH1A1 (0.38) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647137-B1 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF | UNIV CALIFORNIA (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007077333-A2 | USE OF A NEUROPEPTIDE Y ANTAGONIST FOR DAMAGED OR SENSITIVE LIPS | L'OREAL (FR) | 2007-07-12 | — | — | WO | claimed |
| EP-1093803-B1 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI AVENTIS (FR) | 2008-09-17 | — | — | EP | disclosed |
| WO-2003037326-A1 | SOLID PHASE SYNTHESIS OF CHEMICAL LIBRARIES | CORVAS INTERNATIONAL, INC. (US) | 2003-05-08 | — | — | WO | disclosed |
| EP-0838217-B1 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI SYNTHELABO (FR) | 2003-01-15 | — | — | EP | disclosed |
| US-6313128-B1 | CAN BE USED AS LYPOLYSIS/LYPOGENESIS REGULATORS IN THE SKIN WITHOUT, INTERFERRING WITH THE SKIN'S NATURAL FUNCTIONS; FOR THERAPY OF SABORRHEA AND ACNE | SANOFI-SYNTHELABO (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-1132463-A2 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-09-12 | — | — | EP | disclosed |
| EP-1093803-A2 | Cosmetic composition comprising antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-04-25 | — | — | EP | disclosed |
| US-5827853-A | MIXTURE CONTAINING PRODUCT FROM FERMENTATION BY STREPTOMYCES FOR TOPICAL APPLICATION TO SKIN OR HAIR, TO IMPROVE TEXTURE, SURFACE SMOOTHNESS, FIRMNESS | SANOFI (FR) | 1998-10-27 | — | — | US | disclosed |
| US-5807875-A | OBESITY THERAPY | DR. KARL THOMAE GMBH (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0838217-A2 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI (FR) | 1998-04-29 | — | — | EP | disclosed |
| US-5616620-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-04-01 | — | — | US | disclosed |