Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 5/20 | 0.45 |
| ▸ | PPIB | P23284 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | PPIG | Q13427 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 15/20 | 0.42 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895115 | 0.96 | PPID (0.48) | PPIDPPIBPPIAPPIGNPY1R | |
| SCHEMBL7123147 | 0.96 | PPID (0.48) | PPIDPPIBPPIAPPIGNPY1R | |
| Trifluoroacetic Acid SCHEMBL7040972 | 0.91 | NPY1R (0.38) | NPY1RNPFFR1 | |
| Trifluoroacetic Acid SCHEMBL7038182 | 0.91 | NPY1R (0.43) | NPY1RNPFFR1 | |
| Trifluoroacetic Acid SCHEMBL8527977 | 0.91 | NPY1R (0.43) | NPY1R | |
| Trifluoroacetic Acid SCHEMBL7044926 | 0.89 | NPY1R (0.42) | NPY1RNPFFR1 | |
| Trifluoroacetic Acid SCHEMBL8528581 | 0.87 | NPY1R (0.39) | NPY1RNPFFR1 | |
| Trifluoroacetic Acid SCHEMBL7043313 | 0.87 | NPY1R (0.44) | NPY1RNPFFR1 | |
| Trifluoroacetic Acid SCHEMBL649619 | 0.87 | NPY1R (0.43) | NPY1R | |
| Trifluoroacetic Acid SCHEMBL7045238 | 0.87 | NPY1R (0.43) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458684-B1 | THERAPEUTIC HETEROCYCLES AS BRADYKININ B2 RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2008-01-16 | — | — | EP | disclosed |
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |